As the world scientific community plays catch up with COVID-19, which vaccines offer better protection had been a matter of constant debate. As the new variants keep cropping up, the conversation takes new turns.
New data now shows that individuals who received two doses of inactivated virus vaccines (such as COVAXIN) develop lower titres of neutralising antibodies against Omicron. A booster shot -well – produces a boost but an mRNA booster on top of two shots of inactivated vaccines leads to a better response. Data against T cell response is less clear, and there are indications that this response might be more robust.
The data has been nicely summarised in this Nature News and Views article. As D. Akiko Iwasaki, one of the researchers interviewed by the journal says
“The bar keeps being raised by the variants, we’re playing catch up all the time.”